hospital-acquired infection Archives

A C. diff bacterium (green) with iron particles in red, shown in a reconstructed electron tomogram from STEM-EDS. (image courtesy of James McBride)

November 15, 2023

Novel C. diff structures are required for infection, offer new therapeutic targets

Vanderbilt research discovers that iron storage “spheres” inside the bacterium C. diff — the leading cause of hospital-acquired infections — are important for infection in an animal model and could offer new targets for antibacterial drugs.

By Leigh MacMillan

September 12, 2022

Enhancing innate immunity in the lung

Vanderbilt researchers show that a TLR4 agonist improves lung immune response and survival in a mouse model of bacterial pneumonia, supporting the development of this drug to protect against pneumonia in hospitalized patients.

By Leigh MacMillan

December 12, 2019

Wexler receives Helen Hay Whitney Foundation Fellowship

Aaron Wexler, PhD, a research fellow in the Department of Pathology, Microbiology and Immunology, has received a Helen Hay Whitney Foundation Fellowship.