Kidney International

December 5, 2023

Role of immunity in kidney injury hints at a potential therapy: study

Targeting the cytokine IL-22 could be a new therapeutic approach to prevent kidney injury caused by drugs or toxins, Vanderbilt researchers have discovered.

By Bill Snyder
From left, Raymond C. Harris, MD, Shirong Cao, MD, PhD, Ming-Zhi Zhang, MD, MSc, and colleagues are studying the role of inflammation in obesity.
May 12, 2022

Study sheds light on the dark side of obesity

Vanderbilt research that promotes the anti-inflammatory pathway in macrophages could also reduce some of the bad side effects of obesity.

By Bill Snyder
March 14, 2019

Reprogramming cells for kidney repair

Using gene transfer technologies to reprogram adult human kidney cells could lead to novel therapies for chronic kidney disease.

By Kelsey Herbers
November 12, 2015

Immune system a must for kidney repair

A signaling protein that is essential for recovery from acute kidney injury works by increasing the population of tissue-repairing immune cells.

By Lorena Infante
April 16, 2015

Surprising finding in the kidney

TGF-beta signaling in the kidney was thought to be a target for reducing renal fibrosis, but Vanderbilt researchers report that fibrosis still occurs in the absence of TGF-beta signaling.

By VUMC News and Communications
kidney x-ray
June 26, 2014

VU study shows common diabetes drug can slow chronic kidney disease progression

Vanderbilt investigators have demonstrated in two studies that metformin-based treatments delay the onset and progression of chronic kidney disease (CKD) compared with other treatments for diabetes.

By Kathy Whitney
April 17, 2013

‘Longevity’ gene aids kidney survival

A gene associated with cell survival and longevity may protect the kidney from acute injury.
By Leigh MacMillan