medicine

April 17, 2013

‘Longevity’ gene aids kidney survival

A gene associated with cell survival and longevity may protect the kidney from acute injury.

By Leigh MacMillan
April 12, 2013

Lung damage protector

Targeting repair pathways in the lung’s air sacs may be a valuable therapeutic direction for pulmonary fibrosis – the scarring of lung tissue.

By Leigh MacMillan
April 11, 2013

Leukemia culprit’s cellular actions

Overexpression of a gene that is a common culprit in leukemia induces stem cell-like features in T cells, which may enable the cells to become cancerous.

By Leigh MacMillan
April 3, 2013

“Silent” B cells trigger autoimmunity

Immune cells that recognize self antigens (e.g. insulin), but are functionally silent, can trigger autoimmune diseases such as diabetes.

By Leigh MacMillan
March 28, 2013

Acetaminophen: protective in sepsis?

In critically ill patients with sepsis, plasma hemoglobin may be a new indicator of disease severity – and a potential target for treatment with acetaminophen.

By Leigh MacMillan
March 14, 2013

Bacterial resistance breaks bridges

Understanding how bacteria become resistant to quinolone antibiotics could guide strategies for developing new antibacterial drugs.

By Leigh MacMillan
March 6, 2013

Tick-tock – predicting menopause

An ultrasound count of potentially egg-producing follicles could predict the timing of menopause.
By Leigh MacMillan
March 1, 2013

Target for inflammatory bowel disease

The factor STAT6 appears to play a role in the pathogenesis of an inflammatory bowel disease, suggesting it may be a promising target for new treatments.
By Leigh MacMillan
February 20, 2013

Factor CITED in pediatric liver cancer

Vanderbilt researchers report that they have found a factor involved in the persistence of embryonic cells implicated in childhood liver cancer.
By Leigh MacMillan
February 14, 2013

Cell connections key in valve disease

A protein that connects cells together participates in the calcification that occurs in heart valve disease.
By Leigh MacMillan
February 7, 2013

Study tracks genes involved in heart rhythm disorders

A team led by Vanderbilt University investigators has discovered two new genes — both coding for the signaling protein calmodulin — associated with severe early-onset disorders of heart rhythm.
By Leigh MacMillan
February 6, 2013

Linking oxygen, iron and red blood cells

The HIF oxygen-sensing pathway and its responses to low oxygen may be targeted for treatments of anemia and disorders of iron balance.
By Leigh MacMillan
January 31, 2013

Do-it-yourself repair in the kidney

The kidney can mediate its own repair through proliferation of resident immune system cells.
By Leigh MacMillan
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