Molecular Cancer Research Archive — Page 1 of 1

Medical illustration of a human torso showing the trachea, branching airways, and both lungs, with several clustered blue nodules depicted inside the lungs.
November 12, 2020

New therapeutic target for lung cancer

Vanderbilt researchers have identified a new molecular partner — and potential therapeutic target — in a signaling axis that drives lung cancer.

By Sarah E. Glass
Fluorescence microscopy image showing blue-stained cell nuclei surrounded by green cell bodies and branching extensions against a black background; the cells appear separated and variably spread.
February 28, 2019

Protein loss promotes cell migration

The protein kinase STK17A plays a novel role in epithelial cells and its loss may contribute to colorectal cancer invasion and metastasis, Vanderbilt researchers report.

By Leigh MacMillan
Side-by-side fluorescence images of tumors in an animal model: the control tumor on the left has fewer visible blood vessels, while the VEGFR1-high osteosarcoma tumor on the right shows denser vascular networks. Red and green fluorescent structures appear against a black background.
September 3, 2014

Aggressive bone cancers build more blood vessels

A subpopulation of bone cancer cells may be responsible for driving clinically aggressive behavior, suggesting new treatment options.

By Katherine Venmar
Close-up of a person wearing a pink polo shirt with a pink awareness ribbon pinned to the chest.
July 31, 2014

New target for breast cancer therapy

The protein MTBP is overexpressed in an aggressive type of breast cancer, and it regulates another protein implicated in many cancer types, suggesting that it may be a good target for new therapeutics.

By Leigh MacMillan
July 24, 2012

Proteins guard against cancer spread

Targeting immune system proteins may keep prostate cancer from spreading to bone.