Molecular Cancer Research

New therapeutic target for lung cancer

Vanderbilt researchers have identified a new molecular partner — and potential therapeutic target — in a signaling axis that drives lung cancer.

Protein loss promotes cell migration

The protein kinase STK17A plays a novel role in epithelial cells and its loss may contribute to colorectal cancer invasion and metastasis, Vanderbilt researchers report.

Aggressive bone cancers build more blood vessels

A subpopulation of bone cancer cells may be responsible for driving clinically aggressive behavior, suggesting new treatment options.

New target for breast cancer therapy

The protein MTBP is overexpressed in an aggressive type of breast cancer, and it regulates another protein implicated in many cancer types, suggesting that it may be a good target for new therapeutics.

Proteins guard against cancer spread

Targeting immune system proteins may keep prostate cancer from spreading to bone.