NCATS

April 20, 2015

Boosting beta cells in diabetes

New findings suggest that it might be possible to treat diabetes by regenerating insulin-producing beta cells in the pancreas.

February 19, 2015

‘Stretched’ cells promote cancer

Mechanical stress appears to be a critical factor in activating normal tissue-associated fibroblasts to generate cancer-associated fibroblasts.

January 28, 2015

New clue to a devastating disease

New findings suggest a previously unrecognized role for the Sox10 transcription factor in Hirschsprung’s disease, and may lead to improved diagnostic and therapeutic approaches for this disease.

January 23, 2015

New view of dopamine heteromers

Although heteromeric dopamine receptors composed of both D1 and D2 subunits have been proposed to play a role in depression and schizophrenia, recent studies suggest these heteromers do not exist.

January 14, 2015

Inner ear keeps bones strong

Alterations of the vestibular system – the part of our inner ear that controls balance – may contribute to bone loss related to both aging and space travel.

January 13, 2015

Cognitive changes in ‘standing’ syndrome

Patients with orthostatic intolerance – problems when standing – have cognitive changes, even when seated, compared to healthy individuals.