NCATS

A role for blood vessels in delirium?

Dysfunction of the endothelial cells that line blood vessels may contribute to delirium and coma in critically ill patients – and could be a target for therapy.

Lung damage protector

Targeting repair pathways in the lung’s air sacs may be a valuable therapeutic direction for pulmonary fibrosis – the scarring of lung tissue.

Acetaminophen: protective in sepsis?

In critically ill patients with sepsis, plasma hemoglobin may be a new indicator of disease severity – and a potential target for treatment with acetaminophen.

HDL cholesterol impaired in kidney disease

HDL cholesterol is impaired in patients with chronic kidney disease – and may increase their cardiovascular disease risk.

A drug combo for ovarian cancer

Combining another drug with platinum-based chemotherapies may be more effective against ovarian cancer.

Low prenatal alcohol’s brain impact

Even relatively low levels of in utero alcohol exposure impact fetal brain development, and the effects last into adulthood, study finds.

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