NCATS

Pregnant woman holding pill pack
September 20, 2017

NSAIDs, genetics and miscarriage

A certain genetic variant, in combination with the use of anti-inflammatory drugs like aspirin and ibuprofen during early pregnancy, may protect women from miscarriage.

By Leigh MacMillan
August 3, 2017

HDAC3 role in B-cell development

The histone deacetylase HDAC3 is required for the maturation of B cells, white blood cells that produce antibodies.

By Leigh MacMillan
July 20, 2017

Drivers of breast cancer metastasis

Signaling through a complex of proteins called mTORC2 plays a role in breast cancer migration, invasion and metastasis, Vanderbilt researchers reported.

By Leigh MacMillan
July 3, 2017

NOTCH1 role in heart development

The identification of a genetic culprit for hypoplastic left heart syndrome could lead to new treatments for the condition.

By VUMC News and Communications
May 15, 2017

RSV-HRV viral interference

RSV infection reduces the risk of infection with human rhinovirus, which could have implications for vaccine development and prevention strategies for viral respiratory tract infections in infants.

By Leigh MacMillan
Insulin in vials
May 11, 2017

EETs contribute to insulin sensitivity

Interventions that increase circulating levels of compounds called EETs may improve insulin sensitivity and treat hypertension.

By Leigh MacMillan
April 14, 2017

A new mode of DNA repair

Structural details of a protein that removes DNA lesions shed light on fundamental mechanisms of DNA repair.
By Leigh MacMillan
March 20, 2017

Delirium in the ED

Interventions for delirium in the emergency department setting are needed to preserve patients’ long-term function and cognition, Vanderbilt investigators have found.
By Laura Daniel
March 16, 2017

Esophageal cancer complexities

New findings that reveal complex interactions in esophageal adenocarcinoma could lead to diagnostic, prognostic or therapeutic biomarkers.
By VUMC News and Communications
March 8, 2017

Role for mouth microbes in diabetes?

A higher abundance of certain bacterial species in the mouth appears to reduce the risk of type 2 diabetes, Vanderbilt investigators have discovered.
By Leigh MacMillan
March 3, 2017

Mutation raises heart block risk

A newly identified genetic risk factor for heart block after surgery may help guide the course of postoperative care.
By Laura Daniel
January 25, 2017

Flu vaccine response in older adults

High dose flu vaccine boosts the immune response in older adults by increasing activation of certain immune cells.
By Leigh MacMillan
December 8, 2016

Plasmin prevents muscle ‘hardening’ after injury: study

Vanderbilt researchers have made the surprising discovery that the protease plasmin, known for its clot-busting role in the blood, protects soft tissue from turning to bone after severe injuries and certain orthopaedic surgeries.
By Leigh MacMillan