NIH

February 22, 2024

NIH-funded trial to determine if immunomodulation can improve brain and cardiovascular dysfunction in Long COVID

Vanderbilt University Medical Center is working with scientists around the U.S. to launch the first Phase III, multicenter, placebo-controlled trial to determine the effect of immunomodulation on Long COVID.

By Nancy Humphrey
February 1, 2024

A biomarker for early Type 2 diabetes

Genetic analyses suggest that branched chain amino acids may be a sensitive biomarker of early or subclinical Type 2 diabetes and could be used to identify risk and implement preventive measures.

By Bill Snyder
January 16, 2024

Data haul improves immunotherapy response prediction

Vanderbilt biostatisticians have developed an immunotherapy response model that outperforms existing predictive models.

By Paul Govern
January 2, 2024

Team uses COVID-19 to test automated acute disease profiling

An automated solution for creating phenotyping algorithms, PheNorm, worked well to identify symptomatic COVID-19 cases in electronic health records, suggesting that automation could speed high-throughput phenotyping of acute disease.

By Paul Govern
December 29, 2023

Glucose metabolism influences B cell function

Glucose metabolism influences the qualities of activated, mature B cells — white blood cells that are required for antibody-mediated immune responses, Vanderbilt researchers discovered.

By Leigh MacMillan
Mariana Byndloss, DVM, PhD, (left), graduate student Catherine Shelton, and their colleagues discovered that beneficial bacteria in the small intestines produce a compound that protects against obesity. (photo by Erin O. Smith)
December 8, 2023

Gut microbiota metabolite protects against obesity: study

Vanderbilt researchers have discovered that beneficial bacteria in the small intestines produce a compound that protects against obesity.

By Leigh MacMillan
December 8, 2023

You missed a few: a better way to count health care-associated influenza cases

The traditional definition of health care-associated influenza leads to gross undercounting, a Vanderbilt study suggests.
By Paul Govern
December 5, 2023

Role of immunity in kidney injury hints at a potential therapy: study

Targeting the cytokine IL-22 could be a new therapeutic approach to prevent kidney injury caused by drugs or toxins, Vanderbilt researchers have discovered.
By Bill Snyder
December 4, 2023

Study links gene network and pancreatic beta cell defects to Type 2 diabetes

A comprehensive study that integrates multiple analytic approaches has linked a regulatory gene network and functional defects in insulin-producing pancreatic beta cells to Type 2 diabetes.
By Leigh MacMillan and Jill Clendening
November 21, 2023

Commensal gut bacterium protects from severe intestinal infection

The commensal bacterium Turicibacter sanguinis could be used to protect against severe intestinal infections, Vanderbilt researchers discovered.
By Leigh MacMillan
November 16, 2023

Nasty microbe H. pylori has Achilles’ heel

Vanderbilt researchers found that an H. pylori enzyme is essential for colonization of the stomach, suggesting it as a promising therapeutic target for H. pylori infection.
By Paul Govern
November 15, 2023

Study finds many patients don’t seek more health services after receiving genetic screening results

A study by Vanderbilt researchers found that more than half of the patients who receive the results of genetic tests might not be impelled to seek more services than they're already receiving.
By Paul Govern
November 15, 2023

Novel C. diff structures are required for infection, offer new therapeutic targets

Vanderbilt research discovers that iron storage “spheres” inside the bacterium C. diff — the leading cause of hospital-acquired infections — are important for infection in an animal model and could offer new targets for antibacterial drugs.
By Leigh MacMillan
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