Vanderbilt researchers have developed a high-throughput screening method to identify and characterize antigen-specific B cells — potential biomarkers for autoimmune disease and targets for new treatments.

A shift in emotional processing may help women adapt to lower estrogen after menopause —unless they have a history of major depressive disorder, Vanderbilt researchers have found.

Vanderbilt researchers report a comprehensive tissue-specific atlas of protein and mRNA expression for p63 and p73, members of the p53 family signaling network that is the most frequent target of mutations in human cancers.

A high-fat diet disrupts the biology of the gut’s inner lining and its microbial communities — and promotes the production of a metabolite that may contribute to heart disease, according to a study published Aug. 13 in the journal Science.

Vanderbilt neurologists found altered excitability in deep brain structures that they note may drive respiratory dysfunction and sudden death in a rare form of epilepsy.

The motor protein MYO5B, a cause of the congenital intestinal disorder microvillus inclusion disease, does more than move cellular cargo, Vanderbilt researchers have discovered.

Vanderbilt researchers are looking to mRNA populations in podocytes — kidney cells that help filter blood — to help identify potential targets for treating diabetic kidney disease.