NIH

January 23, 2020

HDL-cholesterol and breast cancer risk

Genetic analyses suggest that high circulating HDL-cholesterol levels may increase breast cancer risk — a surprising finding since increased HDL-cholesterol is thought to be healthy.

By Leigh MacMillan
January 23, 2020

VIGH’s Trevathan appointed to NINDS Advisory Council

Edwin Trevathan, MD, MPH, director of the Vanderbilt Institute for Global Health, has been appointed to the Advisory Council for the National Institute for Neurological Diseases and Stroke (NINDS) of the National Institutes of Health.

By Holly Fletcher
January 13, 2020

Vanderbilt-led team discovers new genetic disease and defines underlying mechanism

An international research team has discovered a new genetic syndrome caused by mutation of a single gene and named it CATIFA, an acronym for its core symptoms.

By Leigh MacMillan
January 13, 2020

Zinc uptake by a deadly pathogen

The increasingly antibiotic-resistant bacterium Acinetobacter baumannii requires zinc to cause infection, and Vanderbilt researchers have identified the zinc uptake system it uses.

By Leigh MacMillan
January 10, 2020

Bone matrix changes during aging

Changes to the bone matrix that occur during aging may point to novel targets for treating osteoporosis.

By Leigh MacMillan
January 10, 2020

Structural views of a C. diff toxin

D. Borden Lacy and colleagues used cryo-electron microscopy to define the structure of a C. diff toxin, providing a framework for the design of novel therapeutics.

By Leigh MacMillan
December 20, 2019

Reversing stress-related anxiety

Inhibiting COX-2 — an enzyme associated with inflammation — could provide a novel therapeutic approach for stress-related psychiatric disorders.
By VUMC News and Communications
December 17, 2019

Cell fate signaling

A newly identified protein interaction that affects cell cycle regulation may be an attractive target for cancer therapy.
By Leigh MacMillan
December 16, 2019

Protein dynamics in the beating heart

To study the dynamics of structural proteins in the heart, Vanderbilt investigators generated a cellular tool they expect will be useful for screening drugs that affect heart muscle contraction.
By Leigh MacMillan
December 12, 2019

A new anti-seizure target?

Vanderbilt neurologists have identified a protein modification that could be targeted to reduce neuronal excitability in epilepsy.
By Leigh MacMillan
December 12, 2019

Gregor Mendel would be proud

A computational method that uses hospital billing codes and electronic health records can identify genetic disease cases before clinical teams do.
By Paul Govern
December 11, 2019

VUMC’s Denny selected to lead national ‘All of Us’ program

The National Institutes of Health (NIH) has selected Joshua Denny, MD, MS, vice president of Personalized Medicine at Vanderbilt University Medical Center, to be the chief executive officer of the federal All of Us Research Program.
By Bill Snyder
December 4, 2019

Genetic screen in worms reveals critical step in insulin synthesis

The identification of a protein important for insulin synthesis may hold clues for understanding the pathogenesis of diabetes.
By Leigh MacMillan