NIH Archive — Page 26 of 93

Mud-covered hands scoop wet sediment from shallow, murky water beside clumps of mud.
February 25, 2020

Looking through MudPIT for protein interactions

The identification of novel protein interactions and sites of modification in proteins involved in mRNA translation adds to understanding of a process that is an important therapeutic target.

By Sanjay Mishra
Surreal blue human head surrounded by glowing molecular structures, flowing waveforms, geometric lines, and columns of numbers, evoking science and artificial intelligence.
February 20, 2020

Protein interactions and brain function

Roger Colbran and colleagues have discovered new molecular details about the function of an enzyme with a key role in shaping learning and memory.

By Bill Snyder
Close-up of analog electricity meters with black needles and numbered dials, labeled “KILOWATT.”
February 20, 2020

Transporter mutation alters cell energy

A disease-associated mutation in a transporter protein causes cells to increase energy production, as if they are starving, Vanderbilt researchers have discovered.

By Leigh MacMillan
Two-panel molecular surface rendering labeled A and B. Panel A shows a large multicolored protein complex with a boxed central region and an arrow pointing to panel B. Panel B magnifies the region, with labels β-TF2 and β-TF1 above an outlined area and an arrow identifying a coiled-coil domain.
February 11, 2020

A key to calcium signaling

Erkan Karakas and colleagues used cryo-electron microscopy to determine structural details of a calcium channel protein that has numerous cell signaling roles.

By Sanjay Mishra
Illustration of overlapping purple spherical cells, each with a prominent blue spherical nucleus, against a black background.
February 10, 2020

Imaging breast cancer cell size

A noninvasive MRI approach assesses breast tumor cell size and could be a useful way to evaluate early response to neoadjuvant therapy.

By Leigh MacMillan
Illustration of several teal, curved rod-shaped bacteria with hairlike structures and flagella against a pink-red background.
February 6, 2020

Powering H. pylori pathogenesis

Timothy Cover and colleagues report new insights into the sources of energy used by a bacterial “machine” linked to the pathogenesis of stomach cancer.

By Leigh MacMillan