NIH

Intestinal immune cell interactions

Understanding the roles of various immune cells that reside in the gut lining could shed light on inflammatory bowel diseases.

New role for microtubules in diabetes

Microtubules — part of the cell’s cytoskeleton — regulate the secretion of insulin, suggesting that they may be a new target for treating diabetes.

David Cortez, PhD, left, Petria Thompson, Katherine Amidon, Brandt Eichman, PhD, and colleagues are studying how a DNA repair pathway protein shields sites of damage to avoid mutations.

Team’s study reveals details of new DNA repair pathway

Investigators have discovered how a DNA repair pathway protein shields sites of damage to avoid mutations and maintain genome integrity.

Sex differences in kidney injury

Men are more susceptible to progressive kidney disease than women; new VUMC studies point to differences in the expression and activation of the EGF receptor.

Defective transporter linked to autism

A first-of-its-kind mouse model may help reveal mechanistic underpinnings for the altered behaviors of autism spectrum disorder.

How proteins spread linked to Alzheimer’s disease sex differences

The ways certain proteins spread may help explain why the prevalence of Alzheimer’s is higher in women than in men.

1 29 30 31 32 33 101