NIH

Gut response to fluid flow

Vanderbilt researchers have discovered that microvilli – finger-like projections from cells in the intestine – respond to the shear stress of fluid flow to drive a cellular pathway that regulates nutrient balance.

Calcium intake and colorectal cancer

Calcium intake appears to protect against colorectal cancer in individuals with certain gene variants, Vanderbilt researchers have discovered.

Researchers find novel mechanism of resistance to anti-cancer drugs

Vanderbilt investigators have discovered a novel non-genetic cause of resistance to the targeted anti-cancer therapy cetuximab. Their findings, reported this week in Nature Medicine, suggest a strategy for overcoming this resistance.

New tools to combat kidney fibrosis

Vanderbilt investigators have developed a new mouse model of kidney fibrosis, which provides a platform for identifying new targets and treatment strategies.

A switch for autoimmunity

Vanderbilt investigators have discovered a class of compounds that inhibit a mediator of inflammation and autoimmune disorders, and that could pave the way for development of future therapies.

Boosting sarcoma cell death

A compound identified at Vanderbilt represents a new lead for treating rare, aggressive childhood cancers called Ewing sarcomas.

1 43 44 45 46 47 101