sirtuin

close up of blood vessels

Vascular dysfunction during sepsis

Regulation of the enzyme Sirtuin 1 in blood vessel endothelial cells may drive altered metabolism and vascular dysfunction during sepsis, Vanderbilt researchers have discovered.

‘Longevity’ gene aids kidney survival

A gene associated with cell survival and longevity may protect the kidney from acute injury.

‘Longevity’ gene has role in bone loss

A gene associated with long life participates in the normal regulation of bone remodeling and may have a role in bone loss associated with aging.