spectroscopy

Fueling the MATE transporter

Vanderbilt researchers used spectroscopy to understand how a drug transporter pumps drugs out of cells, findings that are important for developing novel anti-cancer and anti-bacterial drugs that can overcome drug resistance.

New view of transporter dynamics

New insights to the workings of a protein that moves neurotransmitters across the nerve cell membrane could aid the design of more effective antidepressants.

Factor impacts bone toughness

The factor ATF4 has a role in the toughness of bone and its resistance to fracture, suggesting new therapeutic targets.

How ABC transporters move molecules

New views of how transporters move molecules across cell membranes are key to understanding how these proteins impact tumor cell drug resistance and inherited diseases such as cystic fibrosis.

New view of neurotransmitter transport

Dynamic measurements of the bacterial leucine transporter shed light on the transporters that play roles in neuropsychiatric and addiction disorders.