synapse

September 3, 2020

New clue to Alzheimer’s disease

Combining studies of genetically diverse mouse populations and human data led to the identification of a gene associated with cognitive decline and brain changes in Alzheimer’s disease.

By Bill Snyder
Nobel laureate Thomas Südhof, MD, discusses his synapse research at last week’s Discovery Lecture.
October 10, 2019

Nobel laureate Südhof reviews his landmark signaling research

The human brain consists of perhaps as many as 1,000 trillion synapses, which transmit signals from one nerve cell to another with amazing speed, precision and plasticity.

By Bill Snyder
September 18, 2015

Nerve cell remodelers

Vanderbilt investigators have defined a gene expression program that controls the timing of synaptic remodeling – a process that is critical to brain development, learning and memory.

By Leigh MacMillan
May 15, 2012

New clue to ADHD

A rare genetic change adds support to the idea that altered dopamine signaling is a key risk factor for ADHD.

By Bill Snyder