Vsevolod Gurevich

The arrestin-GPCR connection

Understanding details of how arrestins deactivate signaling by G-protein coupled receptors is key to the design of new therapeutics aimed at these cellular “inboxes” that are targeted by up to half of all pharmaceuticals.

Signals from the “conveyor belt”

Vanderbilt researchers propose that cellular signaling pathways are amplified by a “conveyor belt” mechanism that exchanges active and inactive enzymes.

Shining a light on night blindness

Vanderbilt researchers are studying how mutations in the receptor for light, rhodopsin, cause light blindness.

Seeing light receptor’s interactions

Understanding how the main receptor for light interacts with other signaling molecules may inform new pharmaceutical development.

Nobel in Chemistry reveals VU ties that bind

Several Vanderbilt researchers have collaborated with this year’s Nobel Chemistry winners.