william tansey

WIN for blocking cancer growth

William Tansey and colleagues identified proteins that interact with the cancer drug target WDR5 and are important for cancer cell growth.

Protein research seeks to induce tumor regression

Understanding how MYC interacts with WDR5 and other cofactors could lead to the development of new drugs that can effectively block MYC and stop many cancers in their tracks.

Researchers putting the brakes on lethal childhood cancer

Malignant rhabdoid tumor (MRT) is one of the most aggressive and lethal childhood cancers. Although rare — about 20 to 25 new cases are diagnosed annually in the United States — there is no standard effective treatment for the disease, which is driven by loss of an anti-cancer protein called SNF5. The chances are very small that a child will survive a year after MRT diagnosis.

Sweatt, Tansey discuss influence of epigenetics on research

Basic research underway at Vanderbilt University Medical Center is raising hopes that one day it will be possible to reverse memory loss in people with Alzheimer’s disease and stop a major driver of cancer in its tracks.

Vanderbilt’s Sweatt, Tansey set for next Discovery Lecture

How epigenetic regulation of gene transcription forms new memories and triggers cancerous growth is the subject of the next Vanderbilt Discovery Lecture on Oct. 26.

VICC Annual Scientific Retreat slated for May 4

Leading cancer investigators from several prominent universities and laboratories will headline the 2017 Vanderbilt-Ingram Cancer Center Annual Scientific Retreat, to be held Thursday, May 4.