Cancer

Hacker typing on a laptop

Metastatic pancreatic cancer ‘reprograms’ for malignancy

Metastatic pancreatic cancer — cancer that has spread from the pancreas to other tissues and is responsible for most patient deaths — changes its metabolism and is “reprogrammed” for optimal malignancy, according to new findings reported Jan. 16 in Nature Genetics.

Vanderbilt-Ingram Cancer Center supports national HPV vaccination efforts

Nearly 39,000 new cancers associated with the human papillomavirus (HPV) will be diagnosed in the United States this year. Although HPV vaccines can prevent the majority of these cancers, vaccination rates remain low across the country.

color-enhanced cross section of tumor tissue

Softening tumor tissue could aid cancer treatments

Tumors cause the intracellular material surrounding them to stiffen. Softening this protective layer could make existing cancer treatments more effective, according to new research.

Team’s discovery offers new insight on lung cancer risk

Researchers in the Schools of Medicine and Engineering at Vanderbilt University have discovered a proteomic “signature” from the airways of heavy smokers that could lead to better risk assessment and perhaps new ways to stop lung cancer before it starts.

Study links lifestyle factors to formation of high-risk polyps

Lifestyle factors like cigarette smoking and red meat consumption are known to be associated with an increased risk of colon polyps that can lead to colorectal cancer.

Targeting the “un-targetable”

A novel drug that targets the protein RSK blocked aggressive breast cancers from metastasizing in an animal model.

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