Angela Jefferson

New study examines Alzheimer’s disease images and molecular biomarkers

Alzheimer’s disease (AD) involves distinctive wasting away of certain brain regions, such that medical imaging of these regions can distinguish the disease from other subtypes of dementia.

Small vessel disease MRI marker linked to worse cognitive health in older adults

Enlarged perivascular spaces, which are commonly seen on brain MRIs in older adults, have important associations with worse cognitive performance, particularly information processing speed and executive function, according to a new study that challenges historical consideration that perivascular spaces are a harmless imaging marker.

By Holly Fletcher

October 25, 2018

Probing the pathology of impaired cognition

Detecting the neuropathology underlying cognitive impairment by lead to new targeted therapies.

By Bill Snyder

August 30, 2018

Study links aortic stiffness with lower cerebral blood flow

Greater aortic stiffness is related to lower cerebral blood flow, especially among individuals with increased genetic predisposition to Alzheimer’s disease, according to research from Vanderbilt University Medical Center.

By Tom Wilemon

November 8, 2017

Research links heart function to brain’s memory center

Research by a team of Vanderbilt University Medical Center (VUMC) scientists suggests that older people whose hearts pump less blood have blood flow reductions in the temporal lobe regions of the brain, where Alzheimer’s pathology first begins.