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Burroughs Wellcome Fund Archives

New imaging approach offers unprecedented views of staph infection

Mar. 15, 2018—A new integrated imaging approach makes it possible to probe the molecules involved in invasive infections and can be broadly applied to any health or disease state.

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Risk of death in sickle cell disease

Feb. 22, 2017—Two factors commonly used to evaluate patients with sickle cell disease are associated with each other and can predict increased mortality, Vanderbilt researchers have discovered.

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Building the basement membrane

Nov. 21, 2016—Vanderbilt researchers have discovered steps in the regulation of a key enzyme that builds the basement membrane, a structure that undergirds nearly all animal tissues.

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Detect and defend against pathogens

Nov. 4, 2015—Understanding factors, such as the receptor TLR9, that detect and defend against pathogens may lead to therapeutic approaches that promote an effective immune response to treat infections.

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Study identifies C. diff toxin receptor, suggests new treatment approaches

Jun. 4, 2015—Vanderbilt University investigators have identified a cellular receptor for a toxin from Clostridium difficile (“C. diff”) — the leading cause of hospital-acquired diarrhea in the United States.

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Cassat lands Burroughs Wellcome Fund award

Jul. 31, 2014—James Cassat, M.D., Ph.D., assistant professor of Pediatrics and Pathology, Microbiology and Immunology, has received a Burroughs Wellcome Fund (BWF) Career Award for Medical Scientists.

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Defusing ‘C. diff’ infection

Nov. 8, 2013—Clostridium difficile (“C. diff”) infection is a leading cause of hospital-associated diarrhea, and the frequency and severity of infections are on the rise. D. Borden Lacy, Ph.D., associate professor of Pathology, Microbiology and Immunology, and colleagues recently demonstrated that the C. difficile toxin, TcdB, induces rapid cell death of human colon cell lines and pig colonic...

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Burroughs Wellcome Fund lauds Bhave’s research

Aug. 22, 2013—Gautam Bhave, M.D., Ph.D., assistant professor of Medicine, is receiving the Burroughs Wellcome Fund 2013 Career Award for Medical Scientists (CAMS) for his research on the role of peridoxasin and protein halogenation in diabetic nephropathy.

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Medical Center limited submission opportunity: Burroughs Wellcome Fund

Jul. 24, 2013—Vanderbilt may nominate five candidates for the 2014 Career Awards for Medical Scientists, which supports physician-scientists bridging advanced postdoctoral/fellowship training and the early years of faculty service. Grants are $700,000 for a five-year period. Proposals must be in the area of basic biomedical, disease-oriented or translational research. The Burroughs Wellcome Fund encourages nominations from candidates...

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Zinc: a new antibiotic target?

Jan. 17, 2013—It may be possible to fight hospital-acquired pathogens like Acinetobacter baumannii by targeting the bacterium’s need for the nutrient metal zinc.

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On the tail of RSV infection mechanism

Feb. 15, 2012—New details about the life cycle of respiratory syncytial virus (RSV) could aid the development of therapies to combat this leading cause of serious illness in infants and the elderly.

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