Circulation Research (journal)

Clue to salt-sensitive blood pressure found

Despite the well-established link between high salt intake and cardiovascular disease and stroke, the mechanism of SSBP is poorly understood, and it remains an untreatable cardiovascular risk with no widely available diagnostic tool.

Meena Madhur, MD, PhD, Matthew Alexander, MD, PhD, and colleagues are studying how a common genetic change impacts the development of inflammation and high blood pressure.

Study sheds light on the development of inflammation, high blood pressure and resulting kidney damage

The study team included, from left, Mohammad Saleem, PhD, Lale Ertuglu, MD, Annet Kirabo, PhD, and Ashley Pitzer, PhD.

Researchers discover how salt increases blood pressure

A Vanderbilt research team has discovered that activation of a certain protein complex involved in the inflammatory response in immune cells contributes to salt-sensitive hypertension.

Joseph Breeyear, left, Todd Edwards, PhD, and colleagues are studying how high blood pressure genes can improve heart surgery survival in children.

High blood pressure genes improve heart surgery survival in children

Vanderbilt researchers have found that children with a genetic makeup that predicts high blood pressure as adults are more likely to survive congenital heart defect repair surgery.

Vanderbilt study suggests way to prevent rare lung disease

Research by Vanderbilt scientists suggests that it may be possible to prevent or even reverse pulmonary arterial hypertension, a rare, progressive disease characterized by narrowing of and high blood pressure in the small arteries of the lungs.

Going after the ‘heart attack gremlin’

A protein called Gremlin 2 controls the extent of inflammation after heart attack and may be a good therapeutic target.