David Cortez Archives
DNA damage response protein
Oct. 21, 2016—Vanderbilt researchers have determined that a previously uncharacterized protein responds to DNA replication stress and has an essential role in maintaining the integrity of the genome.
VICC investigators in spotlight at AACR conference
May. 19, 2016—A top Vanderbilt-Ingram Cancer Center (VICC) investigator recently met with Vice President Joe Biden regarding the National Cancer Moonshot Initiative, a major national program to identify, fund and accelerate the most promising research leading to cancer cures.
Mechanism of a DNA repair protein
Apr. 15, 2016—Vanderbilt investigators have discovered details about the mechanism of an important DNA repair protein that maintains genome stability.
Copying chromosome caps
Jan. 8, 2016—Telomeres – the caps on the end of chromosomes – are a source of stress for a particular protein involved in copying DNA, a new study reports.
Study helps clarify components of DNA ‘copy machine’
Nov. 12, 2015—Vanderbilt investigators have generated a “parts list” for the molecular machinery that duplicates DNA each time a cell divides. The research has implications for cancer therapies that target components of this machinery.
Repair protein’s DNA recognition motif
May. 23, 2014—Insights into the workings of DNA damage response proteins such as SMARCAL1 could suggest new ways to improve genome integrity and prevent cancer.
VU study sheds new light on DNA replication
Nov. 7, 2013—David Cortez, Ph.D., and his Vanderbilt colleagues report new findings that shed light on fundamental processes involved in DNA replication and have implications for cancer therapies that target these processes.
iPOND method goes fishing for proteins
Mar. 19, 2012—A new tool will allow researchers to identify proteins involved in DNA replication and damage repair, processes that go awry in cancer.
