Department of Anesthesiology

New neurodegeneration culprit

A young woman with a puzzling neurological illness and novel genetic variant pointed investigators to a role for dysregulated protein kinase D1 in neurodegeneration.

Five land ASCI Young Physician-Scientist Awards

Five Vanderbilt University Medical Center faculty members have received Young Physician-Scientist Awards from the American Society of Clinical Investigation (ASCI), an elite honor society of physician-scientists.

Chemo for cancer lowers dementia risk

Cancer chemotherapy lowered risk of Alzheimer’s disease and other neurocognitive disorders that disproportionately affect older people.

Christopher Hughes, MD, left, Pratik Pandharipande, MD, MSCI, and colleagues are studying two drugs recommended for patients receiving mechanical ventilation in the ICU.

Study finds recommended ICU sedatives equally safe, effective

Sedative medications used in intensive care are associated with increased delirium, which is in turn connected with higher medical costs and greater risk of death and ICU-related dementia.

Residents, fellows step up to help care for COVID patients

Following a Thanksgiving surge that led to record numbers of admissions of patients with COVID-19, residents and fellows from multiple disciplines have come together under the direction and supervision of critical care attendings to provide the best care to critically ill patients in Vanderbilt University Medical Center’s COVID-19 Intensive Care Unit.

Large study finds higher burden of acute brain dysfunction for COVID-19 ICU patients

COVID-19 patients admitted to intensive care in the early months of the pandemic were subject to a significantly higher burden of delirium and coma than is typically found in patients with acute respiratory failure. Choice of sedative medications and curbs on family visitation played a role in increasing acute brain dysfunction for these patients.

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