Department of Biochemistry

VU study creates new road map for cellular activity

Human cells are constructed in large part from proteins whose activity can be altered by the incorporation of oxygen in what are known as redox modifications.

Ascano seeks to shed light on cellular stress response

Ebola. Chikungunya. Influenza. What’s to be done about these headline-grabbing, debilitating, often lethal viruses?

Pietenpol named to IOM Cancer Policy Forum

Jennifer Pietenpol, Ph.D., B.F. Byrd Jr. Professor of Oncology and director of Vanderbilt-Ingram Cancer Center, has been named an at-large member of the National Cancer Policy Forum, an advisory group of the Institute of Medicine (IOM) of the National Academies.

Repair protein’s DNA recognition motif

Insights into the workings of DNA damage response proteins such as SMARCAL1 could suggest new ways to improve genome integrity and prevent cancer.

Bypassing DNA damage

Studies of a human polymerase that replicates DNA have provided a complete kinetic and structural framework for understanding how the enzyme accurately bypasses DNA damage.

A new way to target cancer-driver Ras

Vanderbilt researchers have discovered small molecules that turn off cancerous Ras signals in a new way.

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