Hirschsprung disease is a congenital disorder that occurs in approximately 1 in 5,000 babies. Caused by a lack of ENS neurons in the muscles of the colon, Hirschsprung disease disrupts gut motility, resulting in bowel obstruction.

The drug combo pembrolizumab plus axitinib had sustained and durable clinical benefit in more than five years of follow-up. It is a standard-of-care first-line treatment for advanced kidney cancer.

They were part of the Aspirnaut program, which prepares high school and college students, primarily from rural areas, for careers in the STEM fields.

The program was established in 2023 with financial support from the American Cancer Society, and Vanderbilt-Ingram had an inaugural class of four fellows.

Just 15 minutes per day of fast walking reduced the risk of premature death in a low-income and predominantly Black U.S. population.

The video is produced by the research team to explain the results of the study. Findings from the largest genetic analysis of stuttering are published in Nature Genetics; they point to 48 genes associated with stuttering and highlight neurological pathways of risk.

The Center oversees the NIH-funded Diabetes Research and Training Center, now in its 52nd year of continual operation, which advances innovative investigations related to the cause, prevention, treatment and complications of diabetes and obesity.