Department of Medicine

A small-molecule “scavenger” that reduces inflammation and formation of atherosclerotic plaque in blood vessels in mice potentially could lead to a new approach for treating atherosclerosis in humans, according to researchers at Vanderbilt University Medical Center.

After serving as interim chair since Jan. 1, Kimryn Rathmell, MD, PhD, Cornelius Abernathy Craig Professor of Medicine, has been named chair of the Department of Medicine in the Vanderbilt University School of Medicine and Physician-in-Chief for the Vanderbilt University Adult Hospital and Clinics.

Doctors diagnosing pulmonary arterial hypertension (PAH) — elevated pulmonary pressure due to an issue in the small vessels of the lung — rely on a hemodynamic threshold set in the early 1970s to determine whether patients would be candidates for pulmonary vasodilator therapy.

A computational technique that combines the effect of multiple genomic variants has the potential to identify high-risk individuals for cancer prevention.

The first study of appendiceal cancer patterns and survival by race/ethnicity among patients younger than 50 in the U.S. showed survival disparities.

In 2018, Ronnie Kreis began to develop severe heart failure. After being hospitalized multiple times that year near his home in Oliver Springs in East Tennessee, he was told that nothing else could be done.

The multicellular, 3-D structure of human pancreatic islets — the areas of the pancreas containing hormone-producing or endocrine cells — has presented challenges to researchers as they study and manipulate these cells’ function, but Vanderbilt University Medical Center researchers have now developed a pseudoislet system that allows for much easier study of islet function.