Department of Medicine

Oxidative stress and toxic products called isolevuglandins in mitochondria play a role in endothelial dysfunction and hypertension — and getting rid of them with a special “scavenger” molecule has therapeutic potential.

Small RNAs — short stretches of genetic material — from microbes may be playing a role in rheumatoid arthritis and other autoimmune diseases.

Vitamin D protection against colon cancer varies according to parathyroid hormone response, particularly among women.

Jane Freedman, MD, will join Vanderbilt University Medical Center as director of the Division of Cardiovascular Medicine and the physician-in-chief of the Vanderbilt Heart and Vascular Institute, effective Aug. 1.

In a large-scale study of electronic health records, Vanderbilt University Medical Center investigators have determined the prevalence of functional seizures and characterized comorbidities associated with them.

Researchers from the Broad Institute of Harvard and MIT, the National Institutes of Health (NIH) and Vanderbilt University Medical Center for the first time have used a novel genome-editing technique to “rescue” mice from progeria, a rare genetic disease that causes accelerated aging.

Images of cells and tissues are a critical part of biomedical research as they show which molecules or proteins are present and where these molecules are located in the tissue. Using increasingly sophisticated microscopes and imaging approaches, scientists can now look at more than 40 different molecules at once, an approach known as multi-plex imaging, where in the past they could only look at three or four molecules at a time.