Department of Molecular Physiology and Biophysics

Insulin in vials

Matrix remodeling and insulin resistance

The extracellular matrix that surrounds cells plays a role in the development of insulin resistance.

Proton transfer powers multidrug resistance: study

Vanderbilt University researchers and their Belgian colleagues have discovered the mechanism behind a multidrug transporter. Their findings, posted this week by Nature Chemical Biology, could lead to new treatments for multidrug resistant bacterial infections.

Insulin in vials

Relaxin combats insulin resistance

The hormone relaxin may offer a novel approach for treating diet-induced insulin resistance.

Transporter linked to autism risk

Vanderbilt University investigators for the first time have linked a non-inherited, de novo mutation in the dopamine transporter to autism spectrum disorder (ASD).

‘Yo-yo dieting’ inflames fat tissue

Gaining and losing weight during “yo-yo dieting” may contribute to an exaggerated immune response in fat tissue that increases metabolic dysfunction more than steady weight gain alone.

Insulin in vials

Matrix member key to insulin resistance

A component of the extracellular matrix that surrounds cells plays a role in insulin resistance and may be a good therapeutic target.

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