Department of Pathology Microbiology and Immunology

T cells (orange) engage with cancer cells (blue). Halle Borowski, an artist and senior at the College of William and Mary, worked with Drs. Mary Philip and Jess Roetman to create this oil painting, inspired by their research, as part of the Vanderbilt Institute for Infection, Immunology, and Inflammation (VI4) Artist-in-Residence program (https://www.artlab-air.com/).
November 17, 2023

Tumor antigens key to improving cancer immunotherapy: study

Vanderbilt researchers are working to better design immune therapies that attack tumors without also attacking healthy normal tissue in patients.

By Bill Snyder
Mark Denison, MD, and Xiaotao Lu, MS, are among those on a new list of scientists whose papers have been cited the most frequently by other researchers. (photo by Erin O. Smith)
November 15, 2023

Twelve at Vanderbilt are among world’s highly cited researchers

Twelve current investigators at Vanderbilt University Medical Center and Vanderbilt University are on this year’s list of scientists whose papers have been cited the most frequently by other researchers.

By Bill Snyder
A C. diff bacterium (green) with iron particles in red, shown in a reconstructed electron tomogram from STEM-EDS. (image courtesy of James McBride)
November 15, 2023

Novel C. diff structures are required for infection, offer new therapeutic targets

Vanderbilt research discovers that iron storage “spheres” inside the bacterium C. diff — the leading cause of hospital-acquired infections — are important for infection in an animal model and could offer new targets for antibacterial drugs.

By Leigh MacMillan
November 6, 2023

Children’s antibodies highly potent against COVID-19: study

Reporting Nov. 6 in Cell Reports Medicine, Ivelin Georgiev, PhD, and colleagues demonstrated that antibodies isolated from children’s blood samples displayed high levels of neutralization and potency against variants of the COVID-19 virus, SARS-CoV-2, even when the children had not previously been exposed to or vaccinated against those variants.

By Bill Snyder
October 30, 2023

Crowe, Osheroff honored by AAMC

Vanderbilt’s James E. Crowe, Jr, MD, and Neil Osheroff, PhD, are among 12 individuals honored by the Association of American Medical Colleges during its 2023 Awards Recognition Event.

By Bill Snyder
Randika “Randy” Perera, PhD, left, Wenhan Zhu, PhD, Walter Chazin, PhD, Luisella Spiga, PhD, Ryan Fansler and colleagues discovered that beneficial bacteria in the gut impact the competition that occurs between host cells and pathogens for the essential nutrient iron. (photo by Erin O. Smith)
October 27, 2023

Study discovers role for gut bacteria in host-pathogen competition for nutrients

Vanderbilt research shows that commensal gut microbes impact the host-pathogen competition for iron and has implications for therapeutic strategies aimed at preventing pathogens from acquiring essential nutrients.

By Leigh MacMillan
October 24, 2023

Vanderbilt-led team receives 2023 Endeavor Award from The Mark Foundation for Cancer Research

A multidisciplinary team of investigators has received a 2023 Endeavor Award from The Mark Foundation for Cancer Research to support four closely linked projects exploring the fundamental mechanisms that drive the obesity-cancer connection,
By Leigh MacMillan
October 17, 2023

AI predicts blood clot risk in hospitalized children: VUMC study

An artificial intelligence tool developed at Vanderbilt accurately identified pediatric patients at high risk for blood clots in a clinical trial, with no difference in outcomes compared to a control group.
By Bill Snyder
September 25, 2023

Researchers discover molecular signature for aggressive thyroid cancer

A Vanderbilt study found that a molecular signature that predicts aggressive thyroid cancer could help guide treatment approaches for patients.
By Leigh MacMillan
September 22, 2023

Laboratory employees get an early look at new facility

Vanderbilt University Medical Center laboratory employees, their families and many others involved in the ongoing transformation of the Medical Center's laboratories had a first peek at the new 110,000-square-foot core laboratory space during a recent open house.
By Jill Clendening
September 21, 2023

VUMC postdoctoral researcher selected as HHMI Hanna Gray Fellow

Vanderbilt postdoctoral researcher Martin Douglass, PhD, has been named a 2023 Hanna Gray Fellow by the Howard Hughes Medical Institute.
By Anthony Czelusniak
September 13, 2023

James Crowe’s antibody research lands American Society for Microbiology Award

Vanderbilt University Medical Center’s James Crowe Jr., MD, has been named to receive the 2024 American Society for Microbiology Award for Applied and Biotechnological Research.
By Bill Snyder
September 5, 2023

MicroRNAs in immune cells help protect against metabolic defects in obesity: study

Vanderbilt researchers have demonstrated that a cluster of microRNAs — small pieces of RNA that regulate gene expression — work in a type of immune cells called macrophages to help protect against metabolic defects in obesity.
By Leigh MacMillan
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