Division of Clinical Pharmacology

July 12, 2021

Probing statin-associated diseases with genetics

Vanderbilt researchers used genetics tools and biobanks with linked electronic health records to explore the associations between statins and noncardiovascular diseases.

By Leigh MacMillan
From left, Scott Borinstein, MD, PhD, Jonathan Mosley, MD, PhD, and Sara Van Driest, MD, PhD, found that some healthy African Americans are having bone marrow biopsies they don’t need. (photo by Erin O. Smith)
June 28, 2021

Gene variant linked to unnecessary bone marrow biopsies in African Americans

A gene variant that lowers white blood cell levels and is common in individuals with African ancestry contributes to unnecessary bone marrow biopsies, according to a study published June 28 in JAMA Internal Medicine.

By Leigh MacMillan
June 3, 2021

VUMC team discovers new genetic disease

Researchers at Vanderbilt University Medical Center have discovered a new genetic disease that causes a severe form of neurogenic orthostatic hypotension, a rapid drop in blood pressure upon standing that can cause fainting.

By Bill Snyder
(iStock photo)
May 25, 2021

Heat for hypertension in autonomic failure

Heat therapy could offer a novel nonpharmacologic approach for treating the overnight hypertension that affects patients with autonomic failure.

By Leigh MacMillan
April 5, 2021

Codeine metabolizer status in clinical practice

Vanderbilt researchers have developed a response score using genetic and clinical information to aid prescribing of the widely used pain medication codeine.

By Leigh MacMillan
March 15, 2021

Roden honored with Oscar B. Hunter Career Award in Therapeutics

Dan Roden, MD, Senior Vice President for Personalized Medicine at Vanderbilt University Medical Center, received the Oscar B. Hunter Career Award in Therapeutics last week at the virtual annual meeting of the American Society for Clinical Pharmacology and Therapeutics.

By Leigh MacMillan
February 4, 2021

New clue to postural tachycardia

Insight into the pathophysiology of an enigmatic and debilitating disease suggests new treatment approaches.
By Bill Snyder
January 12, 2021

Mitochondrial stress and hypertension

Oxidative stress and toxic products called isolevuglandins in mitochondria play a role in endothelial dysfunction and hypertension — and getting rid of them with a special “scavenger” molecule has therapeutic potential.
By Leigh MacMillan
August 20, 2020

Salt, immune cells and hypertension

Excess dietary salt activates immune cells to induce inflammation and hypertension, supporting current recommendations for low sodium consumption.
By Leigh MacMillan
July 29, 2020

Kirabo receives award from American Heart Association

Annet Kirabo, DVM, MSc, PhD, assistant professor of Medicine and Molecular Physiology and Biophysics, is receiving the 2020 Harry Goldblatt Award for Early Career Investigators from the American Heart Association (AHA).
By Matt Batcheldor
July 9, 2020

Autonomic disorders clinical fellowship created

A new Clinical Fellowship in Autonomic Disorders, administered through the Division of Clinical Pharmacology in the Department of Medicine at Vanderbilt University Medical Center, will be one of only four accredited fellowship programs in autonomic disorders in the country.
By Bill Snyder
July 1, 2020

VUMC-led network to focus on polygenic risk for common diseases

With the aid of a $75 million, five-year grant renewal, the Electronic Medical Records and Genomics Network (eMERGE) will venture beyond its current focus on monogenic disease to scoring research participants’ relative risk for complex heritable diseases such as cardiovascular disease, chronic kidney disease and type 2 diabetes.
By Paul Govern
June 18, 2020

All of Us program launches cloud-based research platform

On May 27, the All of Us Research Program launched the beta version of its cloud-based research platform, the Researcher Workbench.
By Paul Govern
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