Division of Nephrology and Hypertension

New study uses genetic data to support use of thiazide diuretics for kidney stone prevention

A Vanderbilt University Medical Center genetic association study of more than 1 million adults supports the use of the common blood pressure medication thiazide diuretics for kidney stone prevention.

VUMC scientists discover key step to kidney fibrosis

Researchers at Vanderbilt University Medical Center for the first time have shown that activation of the epidermal growth factor receptor (EGFR) is essential for the development of kidney fibrosis, tissue scarring following injury that can lead to kidney failure.

Kidney disease gene also has a protective mutation

African Americans have long been known to be at increased risk of kidney disease due to a dangerous genetic mutation that creates a hole in the kidney cells, but Vanderbilt researchers have now discovered a protective genetic mutation that covers the hole to eliminate the risk.

Vanderbilt investigators land Keck Foundation grant for groundbreaking genetic research

Vanderbilt scientists have received a $1.2 million award from the W. M. Keck Foundation for their groundbreaking project, “Genetic Intolerance Patterns as a Treasure Map to Genes that Define Us as Human.”

Treating kidney injury before it happens

Pretreatment of an animal model with a novel compound called PHAD reduced kidney injury, suggesting it may be a good candidate for preventing kidney injury in surgical patients.

Sex-specific regulation of kidney signals

Links between estrogen signaling and sodium excretion by the kidney could help explain a reduced risk of hypertension in females versus males.

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