Division of Nephrology and Hypertension

April 15, 2021

New insights into kidney development

Integrin-linked kinase, a central component of a complex that coordinates cell signaling involved in migration, proliferation and cell death, plays a role in kidney development and epithelial cell function.

By Bill Snyder
March 25, 2021

Spirituality may help reduce end-stage kidney disease risk

Researchers from Vanderbilt’s Division of Nephrology and Hypertension have identified an under-studied characteristic that may have a protective effect on end-stage kidney disease (ESKD) risk among vulnerable populations.

By Emily Stembridge
close up of blood vessels
October 15, 2020

Brain blood vessel response to hypoxia

The brain’s response to low oxygen — growth and remodeling of blood vessels — involves certain cell types and molecular pathways, Vanderbilt researchers have discovered.

By Leigh MacMillan
October 5, 2020

Clue to diabetic kidney disease

Vanderbilt researchers have identified a signaling pathway that promotes kidney fibrosis in patients with diabetes — and that could be targeted with an existing approved medication.

By Sarah E. Glass
July 30, 2020

Protein study may be key to treating fibrotic diseases

A protein linked to amyotrophic lateral sclerosis (ALS), a progressive neurological disease that causes muscle weakness, may be a key to treating fibrotic disease of the kidneys and other organs, researchers at Vanderbilt University Medical Center reported recently.

By Bill Snyder
William Fissell, MD, has been working on the Kidney Project to create an implantable bioartificial kidney for the last decade.
July 22, 2020

VUMC, UCSF win KidneyX award for implantable home dialysis system

A $500,000 KidneyX prize has been awarded to The Kidney Project — a collaboration between Vanderbilt University Medical Center and University of California, San Francisco (UCSF) — for the development of an implantable dialysis system that would enable patients to safely and effectively treat kidney failure at home.

By Kelsey Herbers
July 13, 2020

Group’s efforts lead to removal of race as a variable in common test of kidney function

A group of Vanderbilt students, residents and faculty — connected through their passion for health equity — have identified and worked together to rectify longstanding concerns about the inappropriate use of race as a variable in the calculation of estimated glomerular filtration rate (eGFR), which estimates a patient’s level of kidney function and helps determine the stage of kidney disease.
By Kathy Whitney
June 4, 2020

Protecting the injured kidney

Leslie Gewin and colleagues have upended conventional dogma about Wnt/beta-catenin signaling in the kidney, finding that it protects against chronic kidney disease rather than promoting it.
By Leigh MacMillan
May 18, 2020

Implant one day may replace dialysis

Vanderbilt researchers used pharmacological manipulations to increase salt and water transport by kidney cells grown in culture, a step necessary for realizing an implantable artificial kidney device.
By Anivarya Kumar
May 12, 2020

Pioneering nephrologist William Stone mourned

William J. Stone, MD, nephrologist and professor of Medicine, emeritus, who retired in December after 50 years as a member of the faculty of the Vanderbilt University School of Medicine, died Monday, May 11, at his home in Nashville. He was 83.
By Bill Snyder
February 18, 2020

Barbershops targeted to improve health of black men

Black men with high blood pressure could benefit from a research study beginning this month to check their vitals while they are getting a haircut at a barbershop.
By Kelsey Herbers
February 13, 2020

Nashville VA dialysis unit named in Stone’s honor

The Nashville Veterans Affairs Medical Center has dedicated its dialysis unit to William Stone, MD, a nephrologist and professor of Medicine at VUMC
By Kelsey Herbers
February 6, 2020

Team tracks integrin’s role in lung function

Beta-1 integrin, a critical component of epithelial extracellular matrix receptors, is essential for normal lung function in adulthood, researchers at VUMC have discovered.
By Bill Snyder
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