eLife (journal)

March 23, 2023

Decoding cell division machinery

Phosphate modification regulates the cell localization of Cdc15, one of the main controllers of cell division, to fine tune the assembly of cell division machinery.

By Caroline Cencer 
October 17, 2019

Microscopic spines connect worm neurons

Worm neurons have microscopic “spines” — where nerve-to-nerve communication happens — that share features with mammalian neurons, supporting the use of worms to study spine genetics and biology.

By Leigh MacMillan
October 11, 2018

Novel genetic study sheds new light on risk of heart attack

Loss of a protein that regulates mitochondrial function can greatly increase the risk of myocardial infarction (heart attack), Vanderbilt scientists reported Oct. 3 in the journal eLife.

By Bill Snyder
November 9, 2017

Advanced imaging tools reveal architecture of cell division machinery

Using super-resolution microscopy tools in the Nikon Center of Excellence, Vanderbilt investigators have determined the molecular architecture of the contractile ring machinery that functions during cell division — a process that is essential for life.

By Leigh MacMillan
April 20, 2017

Ancient sea creature unlocks a mystery of how tissue developed

The dawn of the Animal Kingdom began with a collagen scaffold that enabled the organization of cells into tissues.

By Bill Snyder
Close-up of a woolen knitted texture (blue)
January 19, 2017

Surprising finding by VU team sheds light on fibrotic disease

Integrins are membrane proteins made up of combinations of different “alpha” and “beta” subunits that enable cells throughout the body to interact with their surroundings.

By Bill Snyder
August 2, 2016

Refining neural circuitry

During development, neural circuits are remodeled – some synapses are eliminated and others are strengthened – to produce a mature, functional nervous system.
By Leigh MacMillan
May 12, 2016

COX-2 blocker could help PTSD

COX-2 inhibitors – used clinically to reduce inflammation and pain – may find new applications for treating PTSD and other stress-related psychiatric disorders like major depression.
By Bill Snyder
February 18, 2016

Study explores less invasive way to monitor colorectal cancer

Investigators at Vanderbilt University Medical Center have published research regarding an important feature of colorectal cancer (CRC) that could eventually lead to the development of non-invasive means of monitoring cancer progression. After lung cancer, CRC is the second-most lethal cancer in the United States.
By VUMC News and Communications
August 5, 2014

Technique brings spinal cord neural signaling into focus

Researchers in the Vanderbilt University Institute of Imaging Science have achieved the first conclusive non-invasive measurement of neural signaling in the spinal cords of healthy human volunteers.
By Bill Snyder
June 13, 2014

How ABC transporters move molecules

New views of how transporters move molecules across cell membranes are key to understanding how these proteins impact tumor cell drug resistance and inherited diseases such as cystic fibrosis.
By Leigh MacMillan