epilepsy

Pediatric health conditions, their treatments and the related stress hinder the prefrontal cortex, which is the region of the brain associated with learning, memory and behavior. (istock)

Goal of new tissue-chip research is to assess efficacy of novel epilepsy drugs

An interdisciplinary team of Vanderbilt University researchers has received a two-year, $2-million federal grant to develop an “organ-on-chip” model for two genetic forms of epilepsy.

Asian baby girl getting temperature taken

Heat a trigger for seizures

Elevated body temperature alone can increase vulnerability to fever-induced seizures, even in the absence of infection or inflammation.

Brain image

Predicting brain surgery outcomes

Assessing brain functional and structural connectivity in patients with temporal lobe epilepsy may be a useful way to identify the best candidates for surgical treatment.

newborn baby

New clues emerge in rare form of childhood epilepsy

Researchers at Vanderbilt University Medical Center (VUMC) are one step closer to understanding what causes early-onset epileptic encephalopathy, a rare form of childhood epilepsy that is difficult to treat and has poor developmental outcomes.

brain and lightning

Protein structure and epilepsy severity

Understanding how mutations affect the structure and function of inhibitory neurotransmitter receptors will shed light on the mechanisms underlying some types of epilepsy.

brain and lightning

Culprits in genetic epilepsies

Genetic variation in GABA-A receptors confers risk for inherited forms of epilepsy.

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