immunology

A cell-penetrating peptide developed at Vanderbilt blocks the signaling pathways that lead to lethal shock caused by bacterial infection.

Vanderbilt researchers have discovered that certain immune cells contribute to the development of hypertension, suggesting novel targets for treating the disease.

Drugs such as aspirin and indomethacin may increase sensitivity to airborne allergens by suppressing production of the signaling molecule PGI2, which in turn may offer a new treatment for allergies.

Vanderbilt investigators have discovered a new type of immune cell residing in the intestinal epithelium that may function as a first line of defense against ingested pathogens.

Vanderbilt investigators identify a new therapeutic target for the inflammatory lung disease sarcoidosis.

Understanding how the immune system responds to the respiratory virus HMPV is crucial for developing vaccines and anti-viral treatments.

Understanding how to control the generation of regulatory T cells could have important implications for treating autoimmunity and cancer.