immunology

November 6, 2014

Immune cell activity and melanoma

The activity of a certain factor in immune cells is essential for an anti-tumor response, emphasizing the need to consider the effects of anti-cancer therapies on immune cells.

By VUMC News and Communications
October 28, 2014

Peptide quells “genomic storm”

A cell-penetrating peptide developed at Vanderbilt blocks the signaling pathways that lead to lethal shock caused by bacterial infection.

By T.J. Utset
October 24, 2014

Immune cells’ role in hypertension

Vanderbilt researchers have discovered that certain immune cells contribute to the development of hypertension, suggesting novel targets for treating the disease.

By Leigh MacMillan
October 10, 2014

Aspirin and allergies

Drugs such as aspirin and indomethacin may increase sensitivity to airborne allergens by suppressing production of the signaling molecule PGI2, which in turn may offer a new treatment for allergies.

By VUMC News and Communications
October 9, 2014

Immune cells that guard against ingested pathogens discovered

Vanderbilt investigators have discovered a new type of immune cell residing in the intestinal epithelium that may function as a first line of defense against ingested pathogens.

By Leigh MacMillan
September 25, 2014

A path to sarcoidosis treatment

Vanderbilt investigators identify a new therapeutic target for the inflammatory lung disease sarcoidosis.

By VUMC News and Communications
July 23, 2014

Natural killer cells don’t clear HMPV

Understanding how the immune system responds to the respiratory virus HMPV is crucial for developing vaccines and anti-viral treatments.
By Leigh MacMillan
July 17, 2014

Regulating immune regulators

Understanding how to control the generation of regulatory T cells could have important implications for treating autoimmunity and cancer.
By Leigh MacMillan
July 9, 2014

Study finds ‘hot’ frogs fight off fungal pathogen

Simple heat treatments may give the frog immune system a boost and help it fight off a deadly fungal pathogen, according to a new study published July 10 in the journal Nature.
By Leigh MacMillan
February 12, 2014

Obesity sends immune cells to the brain

Obesity causes peripheral immune cells to move to the brain, where they may contribute to inflammation and the pathophysiology of obesity.
By Leigh MacMillan
January 15, 2014

HIV’s impact on B cells

Understanding how HIV infection affects immune system B cells may guide strategies for vaccine development.
By Leigh MacMillan
October 17, 2013

Frog-killing fungus paralyzes amphibian immune response

A fungus that is killing frogs and other amphibians around the world releases a toxic factor that disables the amphibian immune response, Vanderbilt University investigators report Oct. 18 in the journal Science.
By Leigh MacMillan
August 28, 2013

Probing intestinal immune cell roles

A new in vitro system will allow investigators to explore how immune system T cells develop specialized functions.
By Leigh MacMillan
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