immunology

October 12, 2017

A switch for autoimmunity

Vanderbilt investigators have discovered a class of compounds that inhibit a mediator of inflammation and autoimmune disorders, and that could pave the way for development of future therapies.

By VUMC News and Communications
October 12, 2017

Researcher targets peanut allergies with Cohen Fund support

Scott Smith, M.D., Ph.D., assistant professor of Medicine, has received a 2017 research award from the Stanley Cohen Innovation Fund to test a new therapeutic strategy for peanut allergies. Smith’s research could fundamentally change allergy treatment.

By Leigh MacMillan
September 21, 2017

Excess dietary manganese increases risk of staph infection in heart

Too much dietary manganese — an essential trace mineral found in leafy green vegetables, fruits and nuts — promotes infection of the heart by the bacterium Staphylococcus aureus (“staph”).

By Leigh MacMillan
Lymphocytes attacking cancer cell
August 31, 2017

Pancreatic cancer development

Elevated levels of the factor G-CSF appear to promote the development of aggressive pancreatic cancer, suggesting a new therapeutic approach for this devastating disease.

By Leigh MacMillan
August 4, 2017

An immune regulator of addiction

Although drug addiction is classically studied in a neuron-centric way, Vanderbilt researchers have discovered that the immune system also plays a critical role.

By Sanjay Mishra
August 3, 2017

HDAC3 role in B-cell development

The histone deacetylase HDAC3 is required for the maturation of B cells, white blood cells that produce antibodies.

By Leigh MacMillan
June 29, 2017

Genetics of lung cancer survival

Vanderbilt investigators have conducted a first-of-its-kind genome-wide association study of lung cancer survival in African-Americans.
By Sanjay Mishra
April 19, 2017

Predicting the infection response

Vanderbilt investigators are probing the response to a bacterial toxin as a clinical assessment of immune function.
By Sanjay Mishra
February 16, 2017

Team’s study uncovers cellular responses to bird flu vaccine

New research from Vanderbilt University eavesdrops on gene expression in human immune system cells before and after vaccination against bird flu.
By Paul Govern
February 8, 2017

Pathology of septic shock

The signaling molecule IL-15 promotes septic shock, a life-threatening condition involving organ injury caused by infection.
By Leigh MacMillan
February 2, 2017

New target for chronic infection

An enzyme in macrophage immune cells may be a good target for treating chronic infections, Vanderbilt researchers have discovered.
By VUMC News and Communications
January 25, 2017

Flu vaccine response in older adults

High dose flu vaccine boosts the immune response in older adults by increasing activation of certain immune cells.
By Leigh MacMillan
November 17, 2016

Stem cells promote tolerance

Blood-forming stem cells play a role in immune tolerance and acceptance of organ transplants, Vanderbilt researchers have discovered.
By Leigh MacMillan
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