inflammatory bowel disease (IBD) Archive — Page 2 of 2

bacteria microbiome
August 13, 2019

Host-microbe interactions in the gut

Vanderbilt investigators demonstrated that intestinal cells promote beneficial microbe behavior — the findings support developing microbiota-based therapies for intestinal health.

3D histological illustration of a row of tall columnar epithelial cells, with elongated nuclei and a brush-like apical surface above a purple underlying layer.
July 30, 2019

Intestinal immune cell interactions

Understanding the roles of various immune cells that reside in the gut lining could shed light on inflammatory bowel diseases.

spotlight on a black background
February 28, 2019

Lighting up colorectal cancer

A nanobeacon imaging agent that binds specifically to colorectal cancer cells may aid the early detection of cancer during colonoscopy.

Stylized medical illustration of intertwined intestinal loops glowing orange and red against a dark blue abdominal silhouette, with scattered dark circular markings on the intestines.
July 19, 2018

Novel insights on “leaky” gut

A protein involved in binding cells together helps maintain the integrity of the intestinal mucosa and plays a protective role in ulcerative colitis.

tree roots
November 30, 2017

Lineage tracing in the gut

Vanderbilt investigators have developed an algorithm to classify cell types from experimental data, making it possible to understand how organs develop.

October 26, 2017

Gut response to fluid flow

Vanderbilt researchers have discovered that microvilli – finger-like projections from cells in the intestine – respond to the shear stress of fluid flow to drive a cellular pathway that regulates nutrient balance.