Jeffrey Smith Archives

June 5, 2023

Study discovers that tumor mutation burden predicts survival outcome

The expected course of a patient’s cancer prognosis has traditionally been judged by its type, stage and microscopic aggressiveness, but patients with the same presentation can still have widely divergent outcomes. Researchers from Vanderbilt-Ingram Cancer Center have discovered that differences in tumor mutation burden are a major reason for this divergence.

By Tom Wilemon

March 23, 2020

Study reveals an inherited origin of prostate cancer in families

Vanderbilt researchers have identified haplotypes, ancestral fragments of DNA, that are associated with hereditary prostate cancer (HPC) in a first-of-its-kind genomic study made possible by the study of prostate cancer patients with family histories of the disease.

By Tom Wilemon

March 27, 2014

Study links stem cell gene to prostate cancer susceptibility

A gene on chromosome 8 — in a region of the genome linked to risk for many types of cancer — is particularly associated with prostate cancer susceptibility, Vanderbilt University researchers have found.