jin chen Archives
Breast cancer cells ‘steal’ nutrients from immune cells: study
Apr. 1, 2021—Triple-negative breast cancer cells engage in a “glutamine steal” — outcompeting T cells for the nutrient glutamine and impairing their ability to kill tumor cells, Vanderbilt researchers have discovered.
New therapeutic target for lung cancer
Nov. 12, 2020—Vanderbilt researchers have identified a new molecular partner — and potential therapeutic target — in a signaling axis that drives lung cancer.
A “torque” for tumor blood vessels
Aug. 20, 2020—Vanderbilt scientists have discovered a new target for normalizing tumor blood vessels to improve cancer immunotherapies.
Switching breast cancer off
Apr. 14, 2016—Signaling by a receptor that is overexpressed in aggressive forms of breast cancer has been linked to glutamine metabolism, suggesting new anti-cancer therapeutic targets.
Overcoming lung cancer drug resistance
Feb. 10, 2016—Vanderbilt investigators have discovered a way to overcome the resistance of some lung cancers to certain targeted therapies, which could lead to more effective treatments for lung cancer patients.
Study tracks new lung cancer drug target
Apr. 10, 2014—Researchers at Vanderbilt University have identified a potential new drug target in subtypes of lung cancer that are difficult to treat.
Study tracks how gene may promote lung cancer tumors
Aug. 9, 2012—Vanderbilt-Ingram Cancer Center researchers have identified how one of the genes most commonly mutated in lung cancer may promote such tumors.