Journal of the American Heart Association Archives
Research network yields significant findings related to obesity
Feb. 16, 2023— by Jill Clendening In 2017, Vanderbilt University Medical Center was selected to be one of four U.S. medical centers in a Strategically Focused Research Network (SFRN) on Obesity funded by a four-year, $15 million award from the American Heart Association to study obesity and train future obesity-focused investigators. Now, the findings of the research...
Study finds chronically disrupted sleep may increase risk for heart disease
Feb. 15, 2023—Vanderbilt research found that sleep irregularity — chronically disrupted sleep and highly variable sleep durations night after night — may increase the risk for atherosclerosis.
BMI genetics influence heart function
Jun. 16, 2022—Vanderbilt researchers have discovered that a genetic predisposition to elevated body mass index increases the risk of diastolic dysfunction — a cardiac condition that can lead to heart failure.
Sex & race & door-to-ECG time
Jun. 2, 2022—More than a third of patients presenting at the emergency department with a suspected heart attack have a “delayed” ECG measure of heart function, with Black patients, females and non-English speakers more likely to experience delays.
Vitamin D impact on disease biomarkers
Aug. 10, 2021—In a randomized controlled trial, vitamin D supplementation did not improve biomarkers for cardiovascular and metabolic disease.
Heat for hypertension in autonomic failure
May. 25, 2021—Heat therapy could offer a novel nonpharmacologic approach for treating the overnight hypertension that affects patients with autonomic failure.
HDL and kidney injury after surgery
Jan. 17, 2018—Higher concentrations of high-density lipoproteins — HDL, the “good” cholesterol — may be protective against acute kidney injury after cardiac surgery, Vanderbilt researchers have discovered.
Clue to pulmonary hypertension
Apr. 13, 2017—Vanderbilt investigators have studied the relationship between race, cardiometabolic traits and pulmonary hypertension.
Atrial disease and hypertension links
Dec. 18, 2014—New findings suggest that misfolded proteins accumulate in the heart atria, particularly in patients with hypertension, and may contribute to atrial heart disease.
Viral illness may spur ‘standing up’ disorder
Mar. 13, 2014—Circulating “autoantibodies” possibly triggered by a viral illness may contribute an abnormally rapid heart rate or tachycardia upon standing that affects 500,000 Americans, mostly young women, according to researchers at the University of Oklahoma and Vanderbilt University.
New target for stopping inflammation
Oct. 11, 2013—Importin alpha 5, a member of a family of proteins that “shuttle” other proteins into the nucleus, is a potential new target for drugs to treat inflammatory diseases.
Early study reveals ‘nuclear’ strategy for atherosclerosis
Apr. 18, 2013—Vanderbilt University scientists have discovered a potential new strategy for lowering cholesterol and triglyceride levels and stopping atherosclerosis and fatty liver disease.
