kidney disease

How to build a basement

Understanding the action of a certain enzyme will shed light on basement membrane function, and on disorders ranging from diabetic kidney disease to cancer.

Study: Why one kidney can work as well as two

Vanderbilt University researchers have come closer to solving a mystery that has puzzled scientists for more than a century: after the loss of one kidney, what causes the growth of the remaining kidney to take up the slack?

Surprising finding in the kidney

TGF-beta signaling in the kidney was thought to be a target for reducing renal fibrosis, but Vanderbilt researchers report that fibrosis still occurs in the absence of TGF-beta signaling.

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Kidney disease impacts HDL function

Chronic kidney disease impairs the protective functions of HDL, Vanderbilt researchers report this month.

kidney x-ray

NIH grant spurs diabetic nephropathy research

Diabetic nephropathy, or kidney disease caused by diabetes, is a major source of morbidity and mortality. In the United States, more than 30 percent of patients receiving either dialytic therapy or renal transplantation have end stage renal disease as a result of diabetic nephropathy.

Cholesterol

Major grant spurs deeper look into ‘good cholesterol’

In some cases, HDL, the “good cholesterol,” may not function properly and may actually accelerate atherosclerosis.

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