kidney disease

November 3, 2015

VUMC receives NIH grant to develop artificial kidney

The National Institutes of Health has awarded a four-year, $6 million grant to investigators at Vanderbilt University Medical Center (VUMC) and the University of California at San Francisco (UCSF) to develop an implantable artificial kidney.

By Paul Govern
September 9, 2015

How to build a basement

Understanding the action of a certain enzyme will shed light on basement membrane function, and on disorders ranging from diabetic kidney disease to cancer.

By Sanjay Mishra
June 11, 2015

Study: Why one kidney can work as well as two

Vanderbilt University researchers have come closer to solving a mystery that has puzzled scientists for more than a century: after the loss of one kidney, what causes the growth of the remaining kidney to take up the slack?

By Bill Snyder
April 16, 2015

Surprising finding in the kidney

TGF-beta signaling in the kidney was thought to be a target for reducing renal fibrosis, but Vanderbilt researchers report that fibrosis still occurs in the absence of TGF-beta signaling.

By VUMC News and Communications
iStock Photo
February 11, 2015

Kidney disease impacts HDL function

Chronic kidney disease impairs the protective functions of HDL, Vanderbilt researchers report this month.

By Leigh MacMillan
kidney x-ray
October 30, 2014

NIH grant spurs diabetic nephropathy research

Diabetic nephropathy, or kidney disease caused by diabetes, is a major source of morbidity and mortality. In the United States, more than 30 percent of patients receiving either dialytic therapy or renal transplantation have end stage renal disease as a result of diabetic nephropathy.

By Kathy Whitney
August 21, 2014

Major grant spurs deeper look into ‘good cholesterol’

In some cases, HDL, the "good cholesterol," may not function properly and may actually accelerate atherosclerosis.
By Bill Snyder
August 7, 2014

Study tracks new end-stage renal disease therapy

Researchers in Vanderbilt’s Division of Nephrology conducted a Phase 3 clinical trial to test the safety and efficacy of a new drug to treat patients with end-stage renal disease.
By Kathy Whitney
July 10, 2014

Molecular ‘chat’ holds kidney fibrosis clues

A novel molecular “conversation” regulates kidney fibrosis – the final result of end-stage chronic kidney disease – suggesting new treatment options for this currently irreversible process.
By Leigh MacMillan
June 26, 2014

VU study shows common diabetes drug can slow chronic kidney disease progression

Vanderbilt investigators have demonstrated in two studies that metformin-based treatments delay the onset and progression of chronic kidney disease (CKD) compared with other treatments for diabetes.
By Kathy Whitney
May 29, 2014

New center dedicated to kidney disease

Kidney disease is the eighth most common cause of death in the United States and affects more than 20 million people, yet many people don’t know they have kidney disease because it often develops very slowly and with minimal symptoms. For this reason, kidney disease is often referred to as a silent killer.
By Kathy Whitney
March 19, 2014

Small molecule protects kidney filter

A compound identified at Vanderbilt has therapeutic potential in protecting the kidney filter barrier.
By Bill Snyder
July 11, 2013

Project seeks to create ‘bioartificial’ kidney

Nephrologist William Fissell IV, M.D., associate professor of Medicine and Biomedical Engineering, is intent on creating and mass-producing an implantable bioartificial kidney that can transform quality of life and prospects for survival for people with chronic kidney disease who would otherwise be forced onto dialysis.
By Paul Govern
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