The collaboration will leverage VUMC’s resource platform, including its comprehensive datasets hosted in Vanderbilt’s BioVU collection of DNA and plasma to enable data-driven insights and to accelerate discovery and development.

Carty’s research focuses on nephrogenic diabetes insipidus, a rare kidney condition in which the body produces too much urine, leading to potentially dangerous dehydration.

Eric Kapitbahay, BSN, RN, works on the 7 South Dialysis unit of Vanderbilt University Hospital. He is one of the latest DAISY Award winners at VUMC.

The report supports previous clinical trials that found the GLP-1 receptor agonist drug semaglutide reduced kidney disease progression in patients with Type 2 diabetes.

The project will create the Urinary Stone Disease Hub, known as USDHub, with de-identified patient data from over 230,000 individuals with kidney stone disease across nine health systems in the U.S.

Thiazide diuretics are commonly prescribed to prevent kidney stone recurrence, treat high blood pressure, and clear fluid from the body in conditions such as heart failure.

A kidney protein that responds to low levels of blood potassium — which can cause high blood pressure and cardiovascular problems — may be a target for new therapeutics.