kidney disease Archive — Page 2 of 6

November 21, 2023

VUMC scientists discover key step to kidney fibrosis

Researchers at Vanderbilt University Medical Center for the first time have shown that activation of the epidermal growth factor receptor (EGFR) is essential for the development of kidney fibrosis, tissue scarring following injury that can lead to kidney failure.

By Bill Snyder
October 5, 2023

Kidney disease gene also has a protective mutation

African Americans have long been known to be at increased risk of kidney disease due to a dangerous genetic mutation that creates a hole in the kidney cells, but Vanderbilt researchers have now discovered a protective genetic mutation that covers the hole to eliminate the risk.

By Craig Boerner
May 8, 2023

Improved imaging for kidney disease

Vanderbilt researchers identified optimal MRI parameters for estimating the severity of polycystic kidney disease, a common inherited disorder that can lead to end-stage renal failure.

By Leigh MacMillan
January 19, 2023

Low potassium injures kidney

Vanderbilt researchers have discovered that low dietary potassium causes direct kidney injury, suggesting potential new targets for treating chronic kidney disease.

By Leigh MacMillan
The study team included, from left, Raymond Harris, MD, J.P. Arroyo, MD, PhD, and Gautam Bhave, MD, PhD.
January 5, 2023

VUMC researchers upend dogma about vasopressin production

Vanderbilt investigators have discovered that vasopressin, which has long been thought to be produced only in the brain, is also produced in the kidney.

By Leigh MacMillan
Craig Brooks, PhD, and colleagues are studying a molecular mechanism that promotes chronic kidney disease following kidney injury. (photo by Erin O. Smith)
December 15, 2022

Novel therapeutic target identified for chronic kidney disease

Vanderbilt investigators have discovered a molecular mechanism that promotes chronic kidney disease following kidney injury.

By Leigh MacMillan