Nature Neuroscience (journal)

Research examines genetics of problematic alcohol use

Alcohol use disorder and problematic drinking are genetically correlated with substance use, certain psychiatric illnesses and other neuropsychiatric traits, according to a study involving Vanderbilt University Medical Center researchers.

Study finds ‘frozen’ fear response may underlie PTSD

To explore how fear becomes entrenched, VUMC researchers traveled down the precise neuronal pathways in the brains of mice that trigger fear responses, and which normally extinguish the behaviors once the danger has passed.

Researchers who helped find high-risk genes for schizophrenia included, from left, Quan Wang, PhD, Bingshan Li, PhD, Nancy Cox, PhD, Rui Chen, PhD, Xue Zhong, PhD, Qiang Wei, PhD, and James Sutcliffe, PhD.

Researchers find high-risk genes for schizophrenia

Using a unique computational framework they developed, a team of scientist cyber-sleuths in the Vanderbilt University Department of Molecular Physiology and Biophysics and the Vanderbilt Genetics Institute (VGI) has identified 104 high-risk genes for schizophrenia.

Protein ‘clumping’ linked to severe form of genetic epilepsy

Researchers at Vanderbilt University for the first time have demonstrated in a mouse model that aggregation, the “clumping together” of abnormal proteins, can contribute to a severe form of genetic epilepsy.