Ryan Stark Archives
Persistent inflammatory state found in half of pediatric sepsis deaths: study
Jun. 29, 2023—New research shows that about half of pediatric patients who died of sepsis over the past 20 years at Vanderbilt University Medical Center had evidence of an inflammatory state called persistent inflammation, immunosuppression and catabolism syndrome.
Vascular dysfunction during sepsis
Oct. 25, 2022—Regulation of the enzyme Sirtuin 1 in blood vessel endothelial cells may drive altered metabolism and vascular dysfunction during sepsis, Vanderbilt researchers have discovered.
Immune tolerance in endothelial cells
Jan. 7, 2016—Inducing “tolerance” to bacterial toxins in the endothelial cells that line blood vessels may offer a new approach for preventing the negative consequences of sepsis.
