Sara Van Driest

January 10, 2023

Anti-nausea drug response in children

Genetic variation in a metabolic enzyme was not associated with response to the anti-nausea drug odansetron in children, Vanderbilt researchers report.

By Leigh MacMillan
December 15, 2022

Van Driest to lead All of Us pediatric research

Vanderbilt’s Sara Van Driest, MD, PhD, has assumed a new post as the first-ever director of pediatrics for the National Institutes of Health’s All of Us Research Program, which aims to accelerate the prevention and treatment of illness through precision medicine.

By Christina Echegaray
May 19, 2022

A clue to an adverse drug event in children

Considering metabolic (CYP2D6) enzyme activity score and patient age may aid in determining an individual’s risk for an adverse event with administration of the anti-arrhythmic drug propafenone.

By Joshua Baker
December 16, 2021

Two VUMC papers named among genomic medicine’s top 10

Vanderbilt researchers wrote two of the “top 10” papers representing key advances in genomic medicine published between September 2020 and August 2021.

By Bill Snyder
September 17, 2021

Grant creates center for maternal, pediatric precision therapeutics

Vanderbilt University Medical Center has been awarded a five-year, $6 million grant from the National Institutes of Health to serve as a center of excellence for Maternal and Pediatric Precision in Therapeutics.

By Christina Echegaray
From left, Dan Roden, MD, Ayesha Muhammad, Jonathan Mosley, MD, PhD, and Sara Van Driest, MD, PhD, found that a genome-wide approach can improve the prediction of drug responses.
July 22, 2021

For more precise drug treatments, ‘squeeze’ the genome: study finds

Large-scale studies will be required to identify the complexity of genetic variations that affect how patients respond to a given drug and whether they will have side effects, according to researchers at Vanderbilt University Medical Center.

By Bill Snyder
June 28, 2021

Gene variant linked to unnecessary bone marrow biopsies in African Americans

A gene variant that lowers white blood cell levels and is common in individuals with African ancestry contributes to unnecessary bone marrow biopsies, according to a study published June 28 in JAMA Internal Medicine.
By Leigh MacMillan
April 30, 2020

PREDICT program expands, opens new Genomics Clinic

A new clinic opening at Vanderbilt University Medical Center will help doctors and patients choose the best drugs for their medical conditions based on the patients’ unique genetic makeup.
By Bill Snyder
November 6, 2019

Study finds acid reducers may pose risk for children

The use of acid reducers among children is on the rise and so are potential side effects, which is sparking concern according to a recent study.
By Jessica Pasley
October 3, 2019

Study: personalized decision support affects intensive care

For patients in pediatric intensive care who are at high risk for acute kidney injury (AKI), giving clinicians automated decision support during the electronic order entry process increased the rate of blood testing for AKI by 9%.
By Paul Govern
May 22, 2019

Van Driest lands young investigator award from the American Society for Clinical Pharmacology and Therapeutics

Sara Van Driest, MD, PhD, assistant professor of Pediatrics and Medicine, recently received the 2019 Leon I. Goldberg Early Investigator Award from the American Society of Clinical Pharmacology and Therapeutics.
By Christina Echegaray
February 7, 2019

PheWAS Core helps researchers make sense of electronic health record data

Some biomedical researchers may be unsure about routine electronic health record (EHR) data and how useful it ultimately may prove for drawing meaningful, actionable associations that warrant changes to clinical practice and lead to improved clinical outcomes.
By Paul Govern
May 24, 2018

Study finds acetaminophen helps reduce acute kidney injury risk in children following cardiac surgery

Children who underwent cardiac surgery were less likely to develop acute kidney injury if they had been treated with acetaminophen in the first 48 hours after their procedures, according to a Vanderbilt study just published in JAMA Pediatrics.
By Matt Batcheldor
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