Timothy Hohman Archive

September 9, 2025

Cheating Alzheimer’s

Most people whose brains exhibit Alzheimer’s pathology don’t have the disease; they reach the end of their lives never having exhibited cognitive impairment. A new study examines the genetics of this resilience.

By Paul Govern
January 15, 2025

Alzheimer’s study details abnormal gene expression tied to blood vessel growth

The study sets out how gene expression that drives the formation of new blood vessels exhibits different patterns, cell by cell, in the brains of people with Alzheimer’s disease.

By Paul Govern
November 8, 2022

Alzheimer’s risk factor and cognition

Vanderbilt researchers found that a protein with roles in innate immunity worsens memory at baseline in carriers of APOE-e4, the strongest genetic risk factor for Alzheimer’s disease, further implicating neuroinflammation in cognitive decline.

By Leigh MacMillan
October 1, 2021

VUMC awarded $31.7 million to harmonize Alzheimer’s research data

Vanderbilt University Medical Center has received a $31.7 million federal grant to harmonize research data gathered on human subjects in scores of disparate studies of Alzheimer’s disease and related dementias.

By Paul Govern
September 3, 2020

New clue to Alzheimer’s disease

Combining studies of genetically diverse mouse populations and human data led to the identification of a gene associated with cognitive decline and brain changes in Alzheimer’s disease.

By Bill Snyder
May 7, 2018

Study provides robust evidence of sex differences with Alzheimer’s gene

The APOE gene, the strongest genetic risk factor for Alzheimer’s disease, may play a more prominent role in disease development among women than men, according to new research from the Vanderbilt Memory and Alzheimer’s Center.

By Tom Wilemon