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Timothy Hohman Archives

Alzheimer’s risk factor and cognition

Nov. 8, 2022—Vanderbilt researchers found that a protein with roles in innate immunity worsens memory at baseline in carriers of APOE-e4, the strongest genetic risk factor for Alzheimer’s disease, further implicating neuroinflammation in cognitive decline.

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VUMC awarded $31.7 million to harmonize Alzheimer’s research data

Oct. 1, 2021—Vanderbilt University Medical Center has received a $31.7 million federal grant to harmonize research data gathered on human subjects in scores of disparate studies of Alzheimer’s disease and related dementias.

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New clue to Alzheimer’s disease

Sep. 3, 2020—Combining studies of genetically diverse mouse populations and human data led to the identification of a gene associated with cognitive decline and brain changes in Alzheimer’s disease.

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Study provides robust evidence of sex differences with Alzheimer’s gene

May. 7, 2018—The APOE gene, the strongest genetic risk factor for Alzheimer’s disease, may play a more prominent role in disease development among women than men, according to new research from the Vanderbilt Memory and Alzheimer’s Center.

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Alzheimer’s study establishes way to measure resilience

Nov. 10, 2016—Vanderbilt researchers have established a new measure of resilience to cognitive impairment in people with asymptomatic Alzheimer’s disease.

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Investigators explore African ancestry, Alzheimer’s risk

Apr. 28, 2016—Higher genomic levels of African ancestry are associated with an increased risk for Alzheimer’s disease, a consortium of investigators reported recently in Alzheimer’s & Dementia.

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Study explores genetics behind Alzheimer’s resiliency

Apr. 10, 2014—Autopsies have revealed that some individuals develop the cellular changes indicative of Alzheimer’s disease without ever showing clinical symptoms in their lifetime.

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