uterine fibroids

VUMC, Nigeria teaching hospital to study genetic risk of fibroids based on regional African ancestry

The research team will analyze existing genome-wide association study data and RNA sequencing to compare fibroid development patterns in Nigerian women and U.S. Black women, which could point to targeted therapies and management strategies for affected women.

Calculating risk for uterine fibroids

Vanderbilt researchers have constructed a polygenic risk score for uterine fibroids that will be useful for exploring causes of these benign tumors and identifying novel drug targets and therapies.

Fibroids and preterm birth

In a large, prospective study, Vanderbilt researchers found no association between fibroids and any clinical subtype of preterm birth, supporting a reconsideration of the impression that fibroids increase preterm birth risk.

pregnant belly

Fibroids and birth outcomes

Women with three or more uterine fibroids — non-cancerous growths — during pregnancy are more likely to have infants with reduced birthweight and may need additional surveillance.

Probing the genetics of fibroids

A new study identified multiple genetic locations associated with the size and number of uterine fibroids — common non-cancerous uterine tumors.

pensive pregnant african american woman at home

Vanderbilt-led study disputes link between uterine fibroids and miscarriage risk

A 10-year study, led by Vanderbilt University Medical Center professor of Obstetrics and Gynecology Katherine Hartmann, M.D., Ph.D., disrupts conventional wisdom that uterine fibroids cause miscarriages.