uterine fibroids

New gene discoveries target uterine fibroids

The research is another step toward development of targeted therapies aimed at reducing the incidence and medical burden of this common condition.

VUMC, Nigeria teaching hospital to study genetic risk of fibroids based on regional African ancestry

The research team will analyze existing genome-wide association study data and RNA sequencing to compare fibroid development patterns in Nigerian women and U.S. Black women, which could point to targeted therapies and management strategies for affected women.

By Kristin Centers

April 26, 2022

Calculating risk for uterine fibroids

Vanderbilt researchers have constructed a polygenic risk score for uterine fibroids that will be useful for exploring causes of these benign tumors and identifying novel drug targets and therapies.

By Leigh MacMillan

September 30, 2021

Fibroids and preterm birth

In a large, prospective study, Vanderbilt researchers found no association between fibroids and any clinical subtype of preterm birth, supporting a reconsideration of the impression that fibroids increase preterm birth risk.

By Emily Stembridge

September 8, 2020

Fibroids and birth outcomes

Women with three or more uterine fibroids — non-cancerous growths — during pregnancy are more likely to have infants with reduced birthweight and may need additional surveillance.