Wesley Self

From left, Sean Collins, MD, MSc, Wesley Self, MD, MPH, Jessica Collins, program director, Vanderbilt Coordinating Center, and Matt Shotwell, PhD, play key roles in a now-international clinical trial platform that is investigating therapies aimed at reducing complications in patients hospitalized with COVID-19.
January 5, 2023

VUMC-led COVID-19 clinical trial platform goes international

The ACTIV-4 Host Tissue clinical trial platform, which is designed to investigate therapies targeting the host tissue response to COVID-19 to mitigate lung injury, is now being expanded internationally.

By Bill Snyder
Vials with medication and syringe on blue methacrylate table. Horizontal composition. Top elevated view.
December 16, 2022

Bivalent booster vaccine effective in preventing COVID-19 hospitalization in older adults

The new bivalent mRNA COVID-19 booster vaccines that began being used in September are beneficial in preventing COVID-19-associated hospitalization in persons 65 and over.

By Craig Boerner
Gordon Bernard, MD, is stepping down from his institutional leadership roles next summer to focus on his research interests.
December 16, 2022

VUMC Announces VICTR Leadership Transition

By Bill Snyder
September 22, 2022

Self named co-principal investigator of Vanderbilt’s Clinical and Translational Science Award

Wesley Self, MD, MPH, a physician-scientist at Vanderbilt University Medical Center, has been named co-principal investigator (co-PI) of Vanderbilt’s Clinical and Translational Science Award (CTSA).  

By Bill Snyder
July 7, 2022

Convalescent plasma doesn’t help severely ill COVID patients: study

A Vanderbilt clinical trial shows that convalescent plasma, widely given to severely ill patients hospitalized with COVID-19 during the pandemic, does not improve their ability to survive or recover

By Nancy Humphrey
April 13, 2022

Additional COVID vaccine helps protect transplant patients

Additional booster doses of vaccine against COVID-19 are particularly important for those who are immunosuppressed, namely those who have had solid organ transplants, a new study shows.

By Nancy Humphrey
February 9, 2022

Vanderbilt and CDC research shows third vaccine dose key to preventing omicron hospitalization

Vanderbilt research shows that two doses of an mRNA COVID-19 vaccine result in lower effectiveness for preventing hospitalization for the omicron variant than previous variants. However, importantly, a third (“booster”) vaccine dose significantly improves protection against omicron hospitalization up to 86%.
By Kristin Smart
January 6, 2022

Grant boosts vaccine effectiveness research

By Nancy Humphrey
July 26, 2021

VUMC, NIH launch clinical trial to test novel therapies to protect host tissue against COVID-19

Vanderbilt University Medical Center researchers, supported by the National Institutes of Health (NIH), are leading a nationwide clinical trial to explore the safety and effectiveness of a group of novel drugs designed to protect patients hospitalized with COVID-19 at high risk of poor outcomes.
By Craig Boerner
March 2, 2021

Study to evaluate effectiveness of COVID-19 vaccines in preventing hospitalization

As the Federal Drug Administration (FDA) considers adding a third COVID-19 vaccine to the rollout, a multicenter study led by Vanderbilt University Medical Center will evaluate how effective the vaccines are in preventing hospitalization from COVID-19.
By Kristin Smart
February 5, 2021

Convalescent plasma improved survival in COVID-19 patients with blood cancers

Treatment with convalescent plasma vastly improved the survival rate of patients hospitalized for COVID-19 who also had hematologic malignances that compromise the immune system, according to new data released by the COVID-19 and Cancer Consortium (CCC19).
By Tom Wilemon
November 9, 2020

Hydroxychloroquine does not help patients hospitalized with COVID-19: Study

Findings from a national study published Nov. 9 in the Journal of the American Medical Association (JAMA) “do not support” the use of hydroxychloroquine for the treatment of adult patients hospitalized with COVID-19, the report concludes.
By Bill Snyder
October 29, 2020

Self named VP for Clinical Research Networks and Strategy

Wesley Self, MD, MPH, has been appointed Vice President for Clinical Research Networks and Strategy at Vanderbilt University Medical Center.
By VUMC News and Communications